Dan Quayle (1947-) was an Indiana lawyer and politician who served in the House and Senate before becoming George H. W. Bush's vice president. He served from 1989 to 1993 and participated in administration work involving economic competitiveness, education, space policy, and other issues. After leaving office, Quayle pursued business, writing, and continued involvement in Republican politics.

Al Gore (1948-) was a Tennessee congressman and senator who became Bill Clinton's vice president in 1993 and served two terms. His vice presidency emphasized environmental policy, government reform, and the development of information technology. After leaving office, Gore became a prominent environmental advocate and received the 2007 Nobel Peace Prize jointly with the Intergovernmental Panel on Climate Change.

Mike Pence (1959-) was an Indiana congressman and governor before becoming vice president under Donald Trump. He served from 2017 to 2021 and chaired the White House Coronavirus Task Force while also presiding over the Senate. His vice presidency concluded with his role in the January 6, 2021 certification of the 2020 presidential election.

Barack Obama (1961-) was the 44th president of the United States serving from 2009 to 2017. Before becoming president, he worked as a civil rights lawyer before entering politics in Illinois and later serving in the U.S. Senate. His presidency was defined by the Affordable Care Act, the response to the Great Recession, continuing the War on Terror, and efforts to address social and environmental issues.

Kamala Harris (1964-) was a California prosecutor, attorney general, and U.S. senator before becoming the 49th vice president in 2021. After serving under Joe Biden, she became the Democratic presidential nominee in 2024 and left office in January 2025.

J. D. Vance (1984) was born and raised in Ohio, served in the Marine Corps, became a lawyer and author, and gained national attention through Hillbilly Elegy. He was elected to the U.S. Senate in 2022 and became Donald Trump's running mate in 2024. Vance became the 50th individual to serve as vice president on January 20, 2025, and remains in office as of 2026.